Evaluation of serum extracellular vesicles as noninvasive diagnostic markers of glioma
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Extracellular Vesicles as Neprilysin Delivery Syemory Improvement of Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative brain disorder which has no effective treatment yet due to the blood barrier in the brain that limits the drugs with the potential of disease improvement. Extracellular vesicles (EVs) are biocompatible nanoparticles with a lipid membrane. These vesicles are secreted from various cells such as mesenchymal stem cells (MSCs) and can pass through biol...
متن کاملExtracellular Vesicles as Neprilysin Delivery Syemory Improvement of Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative brain disorder which has no effective treatment yet due to the blood barrier in the brain that limits the drugs with the potential of disease improvement. Extracellular vesicles (EVs) are biocompatible nanoparticles with a lipid membrane. These vesicles are secreted from various cells such as mesenchymal stem cells (MSCs) and can pass through biol...
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Objective(s): Bacterial infection contributes substantially to neonatal morbidity and mortality. Early diagnosis of neonatal sepsis is difficult because clinical signs are non-specific. We have evaluated serum IL-6, 8 and 10 as potential early diagnostic markers of neonatal infection and their relationship to mortality rate and poor prognosis. Materials and Methods : A total ...
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Solid tumors are likely derived from the coevolution of neoplastic cells, stromal components, vasculature, and immune cells (1). As tumors evolve and progress, an array of molecular changes accumulate giving rise to multiple cell subpopulations, each with the ability to divide and mutate further. In addition, neoplastic cell populations are able to modulate the behavior of other types of cells ...
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The state of protein phosphorylation can be a key determinant of cellular physiology such as early-stage cancer, but the development of phosphoproteins in biofluids for disease diagnosis remains elusive. Here we demonstrate a strategy to isolate and identify phosphoproteins in extracellular vesicles (EVs) from human plasma as potential markers to differentiate disease from healthy states. We id...
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ژورنال
عنوان ژورنال: Theranostics
سال: 2019
ISSN: 1838-7640
DOI: 10.7150/thno.33114